Published in Cancer Weekly, October 10th, 2006
"HCC is rare in young children. We attempted to see if immunohistochemical and mutational-analysis studies could demonstrate that deficiency of the canalicular bile acid transporter BSEP and mutation in ABCB11, encoding BSEP, underlay progressive familial intrahepatic cholestasis (PFIC) - or 'neonatal hepatitis,' suggesting PFIC - that was associated with HCC in young children," scientists in England reported.
"We studied 11 cases of pediatric HCC in the setting of PFIC or 'neonatal hepatitis' suggesting PFIC,"...
Want to see the full article?
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Cancer Weekly
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.