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Cancer Treatment

Recent studies from the United States add new data to cancer treatment research

Published in Cancer Weekly, October 10th, 2006

Investigators in the United States have published new cancer treatment data.

Study 1: Prostate cancer angiogenesis increases in response to 12-lipoxygenase regulation.

"12-lipoxygenase utilizes arachidonic acid to synthesize 12(S)-hydroperoxyeicosatetraenoic acid, which is converted to the end product 12(S)-hydroxyeicosatetraenoic acid, an eicosanoid that promotes tumorigenesis and metastasis. Increased expression of 12-lipoxygenase has been documented in a number of carcinomas," scientists writing in the Journal of Biological Chemistry report.

"When overexpressed in human prostate or breast cancer, 12-lipoxygenase promotes...

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