Cancer Therapy

A two-faced protein can stop metastasis or promote it

Published in Cancer Weekly, October 10th, 2006

A protein known to be a key component of the glue that holds cells together also is involved in breaking them apart and promoting their movement when tumors begin to spread to other parts of the body, researchers at Mayo Clinic have found.

The study, published in a recent online issue of the Journal of Cell Biology, helps illuminate the very first steps involved in metastasis, the spread of cancer that makes the disease difficult to treat, and suggests that a future designer drug might be able to block the beginning of this dangerous process, or stop it once it starts.

"Our data show that this one protein, p120 catenin, is a key player in both...

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Source: Cancer Weekly (2006-10-10)

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