Glioma

Researchers' data from the United States and People's Republic of China advance glioma research

Published in Cancer Weekly, October 24th, 2006

Data on glioma are outlined in reports from the United States and People's Republic of China.

Study 1: Patients with recurrent malignant gliomas tolerated a combination of epidermal growth factor receptor (EGFR) and mammalian target of rapamycin (mTOR) inhibitors.

"Malignant gliomas are frequently characterized by amplification of the EGFR and loss of PTEN tumor suppressor gene. Twenty-eight heavily pretreated patients with recurrent malignant gliomas were administered EGFR inhibitors (gefitinib or erlotinib) in combination with the mTOR inhibitor sirolimus," scientists in the United States reported.

"The regimens were reasonably...

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Source: Cancer Weekly (2006-10-24)

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