Cancer Gene Therapy
Ovarian cancer adenovirus-mediated Calponin h1 gene therapy evaluated
Published in Cancer Weekly, October 31st, 2006
"CN h1, one of the family of actin-binding proteins, stabilizes the filaments of actin and modulates various cellular biological phenotypes. Recent studies revealed the close correlation between the invasive tumor spread and the reduced expression of CNh1 and alpha-smooth muscle actin in the surrounding stromal cells.
"The purpose of this study is to evaluate the efficacy of i.p. CNh1 gene therapy against peritoneal dissemination of ovarian cancer," wrote T. Ogura and colleagues, Kyushu...
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Source: Cancer Weekly (2006-10-31)
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