Lung Cancer
Lung cancer cells transfected with hGSTA1 resist doxorubicin-induced apoptosis
Published in Cancer Weekly, November 7th, 2006
"It has been suggested that the alpha-class GSTs protect various cell types from oxidative stress and lipid peroxidation (LPO)," scientists writing in the journal Archives of Biochemistry and Biophysics reported.
"In order to examine the protective role of alpha-class GST isozyme hGSTA1-1 against DOX-induced lipid peroxidation, cytotoxicity, and apoptosis, human SCLC H69 cells were stably transfected with hGSTA1. Immunological...
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Source: Cancer Weekly (2006-11-07)
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