Cancer Vaccines
Studies from Memorial Sloan-Kettering Cancer Center add new findings in the area of cancer vaccines
Published in Cancer Weekly, November 7th, 2006
New research, "DNA immunization against tissue-restricted antigens enhances tumor immunity after allogeneic hemopoietic stem cell transplantation," is the subject of a report. According to a study from the United States, "Malignant relapse remains a major problem for recipients of allogeneic hemopoietic stem cell transplantation (HSCT). We hypothesized that immunization of allogeneic HSCT recipients against tissue-restricted Ags using DNA vaccines would decrease the risk of relapse without enhancing graft-vs-host disease (GVHD)."
"Using the mouse B16 melanoma model, we found that post-HSCT DNA immunization against a single tumor Ag induces tumor rejection that is...
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Source: Cancer Weekly (2006-11-07)
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