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Uveal Melanoma

Uveal melanoma survival predicted by monosomy 3 and largest tumor diameter

Published in Cancer Weekly, November 14th, 2006

Uveal melanoma survival could be predicted by monosomy 3 and largest tumor diameter.

"Uveal melanoma is one of the most frequently occurring primary intraocular malignancies in the Western world. Cytogenetically these tumors are characterized by typical chromosomal losses and gains, such as loss of 1p, 3, and 6q and gain of 6p and 8q," scientists writing in the journal Investigative Ophthalmology & Visual Science reported.

"Whereas most studies focus on known aberrations, in this one, cytogenetic changes were characterized and correlated with clinical and histopathologic parameters," explained E. Kilic and colleagues, Erasmus Medical Center....

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