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Cancer Therapy

Kosan presents encouraging antitumor and safety data on novel epothilone KOS-1584 at EORTC

Published in Cancer Weekly, December 12th, 2006

Kosan Biosciences, Inc., (KOSN) presented what it describes as encouraging antitumor and safety data from two phase I trials of KOS-1584, a second-generation epothilone.

KOS-1584 is being evaluated in two phase I trials using different dosing regimens with the goal of defining the recommended phase II dose and to assess safety, pharmacokinetics, pharmacodynamics, and early evidence of antitumor activity. Data on KOS-1584 were presented in posters at the 18th American Association for Cancer Research (AACR)-U.S. National Cancer Institute (NCI)-European Organization for Research and Treatment of Cancer (EORTC) Symposium on "Molecular Targets and Cancer Therapeutics," in...

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