Lung Cancer

Vandetanib (Zactima) in phase III study for patients with advanced lung cancer

Published in Cancer Weekly, December 12th, 2006

AstraZeneca announced the start of enrollment into a new Phase III study of the novel once-daily oral anti-cancer drug vandetanib (Zactima, ZD6474) as third/fourth line treatment for patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) who have progressed following EGFR TKI therapy.

The study - Study 44 - will be conducted at 208 centers across 23 countries worldwide, and is expected to enroll more than 930 patients. Study 44 will evaluate overall survival with vandetanib 300mg plus best supportive care (BSC) compared with placebo plus BSC in patients with advanced NSCLC, who have previously received treatment with chemotherapy and an...

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Source: Cancer Weekly (2006-12-12)

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