Angiogenesis
Reports outline angiogenesis research from Chinese Academy of Sciences
Published in Cancer Weekly, December 12th, 2006
New research, "Anti-CD146 monoclonal antibody AA98 inhibits angiogenesis via suppression of nuclear factor-kappaB activation," is the subject of a report. According to a study from Beijing, People's Republic of China, "Our previous study showed that an anti-CD146 monoclonal antibody (mAb), AA98, which was raised against the vascular endothelial cells stimulated by a conditioned medium from hepatocarcinoma SMMC 7721 cells (SMMC 7721-CM), inhibited cell migration, angiogenesis, and tumor growth. However, the underlying mechanism was not elucidated."
"The objective of this study was to understand the mechanism by which mAb AA98 inhibits the endothelial cell migration and...
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Source: Cancer Weekly (2006-12-12)
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