Breast Cancer
Retinoblastoma tumor suppressor modifies therapeutic response of breast cancer
Published in Cancer Weekly, December 19th, 2006
Erik Knudsen and colleagues from the University of Cincinnati showed that decreasing the expression of RB in human breast cancer cells increased their ability to proliferate and their tumorigenic potential. The cells from many breast cancer patients express the receptor for the hormone estrogen, and antiestrogen drugs such as tamoxifen are used to limit the growth of cancer cells in these patients.
In this study, decreasing...
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Source: Cancer Weekly (2006-12-19)
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