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Cancer Gene Therapy

Researchers from Sidney Kimmel Cancer Center report on findings in cancer gene therapy

Published in Cancer Weekly, December 26th, 2006

Fresh data on cancer are presented in the report "Tumor necrosis factor-alpha increases reactive oxygen species by inducing spermine oxidase in human lung epithelial cells: a potential mechanism for inflammation-induced carcinogenesis. Inflammation has been implicated in the development of many human epithelial cancers, including those of the stomach, lung, colon, and prostate. Tumor necrosis factor-alpha (TNF-alpha) is a potent pleiotropic, proinflammatory cytokine produced by many cells in response to injury and inflammation," researchers in the United States report.

"Here, we show that TNF-alpha exposure results in increased production of reactive oxygen species...

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