Leukemia

Study shows Sprycel achieved higher cytogenetic responses, longer survival than Gleevec

Published in Cancer Weekly, January 9th, 2007

Bristol-Myers Squibb Company (BMY) announced results of a randomized phase 2 study showing that a substantial number of patients with chronic-phase chronic myelogenous leukemia (CML) resistant to Gleevec achieved cytogenetic and hematologic responses by 3 months and maintained these responses through one year when treated with Sprycel.

The open-label, multicenter international trial was designed to examine the efficacy and safety of Sprycel at 70 mg twice daily or an increased dose of Gleevec to 800 mg/day (patients enrolled in the trial had been previously treated with Gleevec less than or equal to 600 mg/day). Results were presented at the 48th Annual Meeting and...

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Source: Cancer Weekly (2007-01-09)

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