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Cancer Gene Therapy

Data on cancer gene therapy discussed by researchers at Fudan University, Department of Pharmaceutics

Published in Cancer Weekly, January 9th, 2007

A report, "Cationic albumin-conjugated pegylated nanoparticles allow gene delivery into brain tumors via intravenous administration," is newly published data in Cancer Research. According to a study from Shanghai, People's Republic of China, "S with malignant gliomas have a poor prognosis because these tumors do not respond well to conventional treatments. Studies of glioma xenografts suggest that they may be amenable to gene therapy with cytotoxic genes, such as the proapoptotic Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand (Apo2L/TRAIL)."

"Gene therapy of gliomas ideally employs i.v. given vectors, thus excluding viral vectors as they cannot...

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