Cancer Gene Therapy
Research on cancer gene therapy published by scientists at University Children's Hospital
Published in Cancer Weekly, January 16th, 2007
Fresh data on cancer are presented in the report "Enriching suicide gene bearing tumor cells for an increased bystander effect." According to a study from Ulm, Germany, "The success of cancer gene therapies requiring in vivo gene transfer is severely hampered by the low efficacy of gene transfer, which has been difficult to improve. We therefore established a novel strategy to increase the share of transduced cells post gene transfer."
"We hypothesized that in vivo selection of tumor cells transduced with a suicide gene effectively enriches these cells within a tumor, thus allowing for an increased bystander effect after the prodrug is given, leading to enhanced...
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Source: Cancer Weekly (2007-01-16)
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