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Cancer Gene Therapy

Data from University of South Alabama, Cancer Institute provide new insights into cancer gene therapy

Published in Cancer Weekly, January 16th, 2007

Data detailed in "Association of insulin-like growth factor binding protein-3 expression with melanoma progression" have been presented. "Previous studies from our laboratory have identified several endothelial cell-associated marker genes implicated in human melanoma metastasis via tumor vasculogenic mimicry. In this study, we used dual model systems composed of melanoma cell lines and clinical melanoma samples to validate the importance of insulin-like growth factor binding protein-3 (IGFBP-3) as a marker involved in disease progression," scientists in the United States report.

"Gene expression analysis was done using a microarray approach for both primary and...

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