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Cancer Gene Therapy

Studies from Stony Brook University describe new findings in cancer gene therapy

Published in Cancer Weekly, January 16th, 2007

A report, "Conversion of a tumor-binding peptide identified by phage display to a functional chimeric T cell antigen receptor," is newly published data in Cancer Gene Therapy. "Adoptive transfer of ex vivo expanded tumor-specific T cells is a promising therapeutic modality for promoting or augmenting antitumor immunity. Several groups, including ours, are developing antigen receptor gene transfer strategies as a means of generating effector cells for adoptive therapy," investigators in the United States report.

"Chimeric antigen receptors (CARs) have been described that use single-chain antibodies or cytokine ligands as tumor targeting domains. Here, we describe the...

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