Cancer Gene Therapy
New cancer gene therapy study findings have been published by scientists at Johns Hopkins University, Department of Pathology
Published in Cancer Weekly, January 16th, 2007
Researchers detail in "Single-walled carbon nanotubes-mediated in vivo and in vitro delivery of siRNA into antigen-presenting cells," new data in cancer. According to recent research published in the journal Gene Therapy, "Antigen-presenting cells such as dendritic cells (DCs) play a critical role in inducing and regulating immune responses. One effective strategy for DC-based immunotherapy is to regulate maturation and function of DC."
"In this study, we apply single-walled carbon nanotubes (SWNTs) to carry small interfering RNA (siRNA) to reach, enter and genetically modify DCs in vivo. We prepared positively charged SWNTs (SWNTs+) using 1,6-diaminohexane which...
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Source: Cancer Weekly (2007-01-16)
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