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Biological Chemistry

Investigators at University of California, Jonsson Comprehensive Cancer Center release new data on biological chemistry

Published in Cancer Weekly, January 30th, 2007

New investigation results, "Identifying target genes of the aryl hydrocarbon receptor nuclear translocator (Arnt) using DNA microarray analysis," are detailed in a study published in Biological Chemistry. According to recent research from the United States, "The aryl hydrocarbon receptor nuclear translocator (Arnt) is a basic helix-loop-helix (bHLH) protein that also contains a Per-Arnt-Sim (PAS) domain. In addition to forming heterodimers with many other bHLH-PAS proteins, including the aryl hydrocarbon receptor (AhR) and hypoxia-inducible factors 1alpha, 2alpha and 3alpha, Arnt can also form homodimers when expressed from its cDNA in vitro or in vivo."

"However,...

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