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Cancer Vaccines

Researchers' work from Jikei University focuses on cancer vaccines

Published in Cancer Weekly, January 30th, 2007

Data detailed in "Streptococcal preparation OK-432 promotes fusion efficiency and enhances induction of antigen-specific CTL by fusions of dendritic cells and colorectal cancer cells" have been presented. According to recent research from Tokyo, Japan, "Dendritic/tumor fusion cell (FC) vaccine is an effective approach for various types of cancer but has not yet been standardized. Antitumor activity can be modulated by different mechanisms such as dendritic cell (DC) maturation state."

"This study addressed optimal strategies for FC preparations to enhance Ag-specific CTL activity. We have created three types of FC preparations by alternating fusion cell partners: 1)...

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