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Lung Cancer

Dual gene therapy suppresses lung cancer in preclinical test

Published in Cancer Weekly, February 6th, 2007

Combination gene therapy delivered in lipid-based nanoparticles drastically reduces the number and size of human non-small cell lung cancer tumors in mice, researchers at The University of Texas M. D. Anderson Cancer Center and the University of Texas Southwestern Medical Center report in a recent edition of Cancer Research.

Two tumor-suppressing genes given intravenously reduced cancer separately but had their most powerful effect when administered together, cutting the number of tumors per mouse by 75% and the weight of tumors by 80%.

"In cancer treatment we have combination chemotherapy, and we also combine different modes of therapy -...

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