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Cancer Gene Therapy

Data on cancer gene therapy detailed by researchers at University of Maryland, Department of Radiation Oncology

Published in Cancer Weekly, February 13th, 2007

New research, "Radiosensitization of head/neck squamous cell carcinoma by adenovirus-mediated expression of the Nbs1 protein," is the subject of a report. According to recent research from the United States, "Local failure and toxicity to adjacent critical structures is a significant problem in radiation therapy of cancers of the head and neck. We are developing a gene therapy based method of sensitizing head/neck squamous cell carcinoma (HNSCC) to radiation treatment."

"As patients with the rare hereditary disorder, Nijmegen breakage syndrome, show radiation sensitivity we hypothesized that tumor-specific disruption of the function of the Nbs1 protein would lead to...

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