Cancer Gene Therapy
Data on cancer gene therapy published by researchers at University of Brescia
Published in Cancer Weekly, February 13th, 2007
New research, "RNA interference against urokinase in hepatocellular carcinoma xenografts in nude mice," is the subject of a report. According to recent research from Brescia, Italy, "The serine protease urokinase-type plasminogen activator (u-PA) is overexpressed in hepatocellular carcinoma (HCC) and its expression level is inversely correlated with the patients' survival. The purpose of this study was to examine the effects of vector-based RNA interference (RNAi) of u-PA on the growth of human HCC xenografts in nude mice in order to investigate the role of u-PA in human HCC."
"Our results showed that the subcutaneous injection of small interfering RNAs (siRNA) u-PA...
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Source: Cancer Weekly (2007-02-13)
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