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Brain Cancer

Callisto Pharmaceutical's Degrasyn class has potential to treat brain tumors

Published in Cancer Weekly, February 20th, 2007

Callisto Pharmaceuticals, Inc. announced a recent publication by a research group at the University of Texas M. D. Anderson Cancer Center on a Degrasyn (STAT3 Pathway Inhibitor) drug candidate showing promise as a therapeutic agent to treat malignant gliomas - brain tumors.

STAT3 pathway inhibitors are a new class of drugs that were licensed to Callisto Pharmaceuticals from The University of Texas M. D. Anderson Cancer Center. The report, published in the journal Oncogene, describes studies with WP1066 on human malignant glioma (brain tumor) cells and in a mouse model of human brain cancer. Notably, WP1066 administered to mice significantly inhibited the growth...

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