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Cancer Weekly

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Cancer Gene Therapy



Studies from University of North Carolina, Lineberger Comprehensive Cancer Center have provided new information about cancer gene therapy



February 27th, 2007

A new study, "MUC1 induced by Epstein-Barr virus latent membrane protein 1 causes dissociation of the cell-matrix interaction and cellular invasiveness via STAT signaling," is now available. According to a study from the United States, "Disruption of cellular adhesion is an essential pathobiologic step leading to tumor dissemination. Mucin 1 (MUC1) is a mucinous glycoprotein expressed at the surfaces of epithelial cells in many tissues and their carcinomas."

"MUC1 plays crucial roles in tumor invasion and metastasis, especially in opposing cell adhesion. We have shown that virus infection, specifically by the human tumor virus Epstein-Barr virus (EBV) induces a spectrum...


Source: Cancer Weekly (2007-02-27)

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