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Cancer Vaccines
Scientists at Charite University discuss research in cancer vaccines
February 27th, 2007
New investigation results, "Addition of GM-CSF to a peptide/KLH vaccine results in increased frequencies of CXCR3-expressing KLH-specific T cells," are detailed in a study published in Cancer Immunology, Immunotherapy. According to a study from Berlin, Germany, "T-cell trafficking is determined by expression patterns of chemokine receptors. The chemokine receptor CXCR3 is expressed on a subpopulation of type 1 T cells and plays an important role for migration of T cells into inflamed and tumor tissues." "Here, we studied the chemokine receptor expression on specific T cells generated against the neoantigen keyhole limpet hemocyanin (KLH) in patients who had been...
Source: Cancer Weekly (2007-02-27)
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