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Cancer Vaccines
Scientists at Veterans Affairs Medical Center publish research in cancer vaccines
February 27th, 2007
Scientists discuss in "Antigenic profiling of glioma cells to generate allogeneic vaccines or dendritic cell-based therapeutics" new findings in cancer. "Allogeneic glioma cell lines that are partially matched to the patient at class I human leukocyte antigen (HLA) loci and that display tumor-associated antigens (TAA) or antigenic precursors [tumor antigen precursor proteins (TAPP)] could be used for generating whole tumor cell vaccines or, alternatively, for extraction of TAA peptides to make autologous dendritic cell vaccines. Twenty human glioma cell lines were characterized by molecular phenotyping and by flow cytometry for HLA class I antigen expression," scientists writing in the...
Source: Cancer Weekly (2007-02-27)
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