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Cancer Weekly

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Leukemia Gene Therapy



Research on leukemia gene therapy reported by scientists at Wayne State University, Barbara Ann Karmanos Cancer Institute



February 27th, 2007

Current study results from the report, "Prognostic role of the reduced folate carrier, the major membrane transporter for methotrexate, in childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group," have been published. According to recent research from the United States, "The value of measuring expression of individual genes relevant to particular chemotherapy drugs and encoding metabolizing enzymes, transporters, or drug targets, as predictors of treatment response and outcome in pediatric acute lymphoblastic leukemia (ALL), remains controversial. In a case-control population of 91 pediatric B-precursor ALL patients [42 relapsed within 4 years (cases) and 49 did...


Source: Cancer Weekly (2007-02-27)

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