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Cancer Weekly

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Business Update



Enzon receives U.S. FDA clearance of HIF-1 alpha Investigational New Drug Application



February 27th, 2007

Enzon Pharmaceuticals, Inc. (ENZN) announced that the U.S. Food and Drug Administration (FDA) has approved the Investigational New Drug (IND) application for its HIF-1 alpha (hypoxia-inducible factor 1 alpha) antagonist, a highly-visible, well-validated target in many cancer types, including common solid tumors.

The company plans to initiate a phase I trial in the first half of 2007.

"This marks an important milestone for Enzon as we continue to focus our efforts on important oncology therapies," said Jeffrey Buchalter, chairman and chief executive officer of the company. "The continued advancement of the HIF-1 alpha program demonstrates our...


Source: Cancer Weekly (2007-02-27)

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