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Cancer Research

Weizmann Institute scientists discover genes that can slow cell division and may fight cancer

Published in Cancer Weekly, March 13th, 2007

Cancer cells differ from normal cells in, among other things, the way they divide. When a normal cell complies with a signal telling it to divide, it also begins to activate a "braking system" that eventually stops cell division and returns the cell to a resting state. When that braking system is faulty, uncontrolled cell division and the growth of cancer can result. Weizmann Institute scientists studied this system of brakes, and identified a number of the genes involved.

According to the study's findings, which appeared in Nature Genetics online on February 25, aberrations in the activities of these genes are tied to certain types of cancer, as well as to the relative...

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