Cancer Gene Therapy
Researchers from University Children's Hospital report on findings in cancer gene therapy
Published in Cancer Weekly, March 13th, 2007
Researchers detail in "Human blood late outgrowth endothelial cells for gene therapy of cancer: determinants of efficacy," new data in cancer gene therapy. "Human adult blood late outgrowth endothelial cells (BOECs) are potential yet untested cellular vehicles to target tumor-cytotoxic effectors to tumors. We show that, following intravenous injection into irradiated mice, BOECs home to Lewis lung carcinoma (LLC) lung metastases, but less so to liver or kidney metastases," scientists in Ulm, Germany report.
"BOECs targeted most but not all of the lung metastases, to a different degree. While most of the homed BOECs took up an extravascular position, some integrated into...
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Source: Cancer Weekly (2007-03-13)
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