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Cancer Gene Therapy

Data on cancer gene therapy described by researchers at University of Tokyo

Published in Cancer Weekly, April 3rd, 2007

Investigators publish new data in the report "Single-injection ornithine decarboxylase-directed antisense therapy using atelocollagen to suppress human cancer growth. Substantial evidence supports a direct role of ornithine decarboxylase (ODC) in the development and maintenance of human tumors. Although antisense oligonucleotide therapy targeting various genes are useful for cancer treatment, 1 of the major limitations is the problem of delivery," scientists in Tokyo, Japan report.

"A novel antisense oligonucleotide delivery method is described that allows prolonged sustainment and release of ODC antisense oligonucleotides in vivo using atelocollagen. The effect of ODC...

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