Cancer Gene Therapy
New findings from Okayama University in the area of cancer gene therapy described
Published in Cancer Weekly, April 3rd, 2007
Data detailed in "Fine deletion mapping of chromosome 2q21-37 shows three preferentially deleted regions in oral cancer" have been presented. "We analysed the loss of heterozygosity (LOH) of long arm of chromosome 2 by using 16 polymorphic microsatellite markers in 39 matched oral normal and cancer tissues, and defined the deletional mapping of the region with putative tumor suppressor genes. LOH was detected at least one location in 33 of 39 (85%) tumor tissues," scientists in Japan report.
"Frequent deletions were detected at the locations of microsatellite markers, D2S2304 (35%), D2S111 (40%), D2S155 (35%), D2S1327 (29%), D2S164 (29%), D2S125 (68%) and D2S140 (32%)....
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Source: Cancer Weekly (2007-04-03)
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