Cancer Gene Therapy
Research on cancer gene therapy detailed by scientists at Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Published in Cancer Weekly, April 3rd, 2007
New investigation results, "Human retinoblastoma is not caused by known pRb-inactivating human DNA tumor viruses," are detailed in a study published in International Journal of Cancer. "Retinoblastomas occur as the consequence of inactivation of the tumor suppressor retinoblastoma protein (pRb), classically upon biallelic inactivation of the RB1 gene locus. Recently, human papillomavirus (HPV) genomic DNA has been detected in retinoblastomas," scientists in the United States report.
"To investigate the possibility that oncoproteins encoded by pRb-inactivating DNA tumor viruses play a role in the pathogenesis of human retinoblastoma, 40 fresh-frozen tumors were...
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Source: Cancer Weekly (2007-04-03)
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