Hepatocellular Cancer
New hepatocellular cancer research reported from Jikei University, Department of Pathology
Published in Cancer Weekly, April 24th, 2007
Research findings, "Frequent loss of heterozygosity in two distinct regions, 8p23.1 and 8p22, in hepatocellular carcinoma," are discussed in a new report. In this recent report, researchers in Tokyo, Japan conducted a study "To identify the precise location of putative tumor suppressor genes (TSGs) on the short arm of chromosome 8 in patients with hepatocellular carcinoma (HCC). We used 16 microsatellite markers informative in Japanese patients, which were selected from 61 published markers, on 8p, to analyze the frequency of loss of heterozygosity (LOH) in each region in 33 cases (56 lesions) of HCC."
"The frequency of LOH at 8p23.2-21 with at least one marker was 63%...
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Source: Cancer Weekly (2007-04-24)
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