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Antisense Technology
Novosom AG acquires exclusive option for CD40-targeted antisense inhibitors from Isis Pharmaceuticals
May 1st, 2007
Novosom AG today announced that it has purchased an exclusive option from Isis Pharmaceuticals, Inc. that, if exercised within six months, enables it to acquire an exclusive, worldwide license to antisense inhibitors targeting the CD40 membrane protein for all indications. CD40 is a validated target for both inflammatory diseases and B-cell cancers and Novosom plans to target CD40 for indications such as Crohn's disease, transplant, rheumatoid arthritis, cancer and multiple sclerosis. If acquired, the license from Isis would include rights to the target and to oligonucleotides targeting CD40 and incorporating Isis' second generation antisense chemistry, 2' MOE oligonucleotides in exchange...
Source: Cancer Weekly (2007-05-01)
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