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Cancer
Research findings from University of New Mexico update understanding of cancer
May 1st, 2007
Data detailed in "Assessment of the frequency of allelic imbalance in human tissue using a multiplex polymerase chain reaction system" have been presented. "Genomic instability can generate chromosome breakage and fusion randomly throughout the genome, frequently resulting in allelic imbalance, a deviation from the normal 1:1 ratio of maternal and paternal alleles. Allelic imbalance reflects the karyotypic complexity of the cancer genome," scientists writing in the Journal of Molecular Diagnostics report. "Therefore, it is reasonable to speculate that tissues with more sites of allelic imbalance have a greater likelihood of having disruption of any of the...
Source: Cancer Weekly (2007-05-01)
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