Angiogenesis
Research from Kitasato University, Department of Public Health yields new data on angiogenesis
Published in Cancer Weekly, May 8th, 2007
A report, "Androgen-dependent gene expression of prostate-specific antigen is enhanced synergistically by hypoxia in human prostate cancer cells," is newly published data in Molecular Cancer Research. According to recent research from Japan, "The androgen receptor (AR) is implicated in prostate cancer growth, progression, and angiogenesis. Hypoxia-inducible factor-1 (HIF-1), which transcriptionally regulates hypoxia-inducible angiogenic factors, is up-regulated in prostate cancers compared with adjacent normal tissues."
"HIF-1 may be involved in prostate cancer as well as the AR, but the involvement of HIF-1 in prostate cancer angiogenesis and progression has not...
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Source: Cancer Weekly (2007-05-08)
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