Breast Cancer Genetics
New breast cancer genetics study findings have been reported from Istanbul University, Oncology Institute
Published in Cancer Weekly, May 8th, 2007
Investigators publish new data in the report "Functional polymorphism of thymidylate synthase, but not of the COMT and IL-1B genes, is associated with breast cancer. Polymorphic variations may affect the rate of gene transcription, the stability of the mRNA, or the quantity and activity of the resulting protein. In this study we evaluated the association between the interleukin-1B C-31T, catechol-O-methyltransferase Val158Met, and thymidylate synthase (TS) 1494del6 polymorphisms and breast cancer," scientists in Istanbul, Turkey report.
"Each genetic polymorphism was investigated by polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) analysis....
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Source: Cancer Weekly (2007-05-08)
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