Drug Resistance
New drug resistance data have been reported by researchers at Wayne State University, Barbara Ann Karmanos Cancer Institute
Published in Cancer Weekly, May 8th, 2007
A report, "The proteasome as a potential target for novel anticancer drugs and chemosensitizers," is newly published data in Drug Resistance Updates. According to a study from the United States, "A major challenge in cancer therapy is tumor drug resistance. To overcome it, it is essential to understand the mechanisms and identify the molecules involved, so that they can be specifically targeted in combination therapies."
"The proteasome is such a validated target: it plays a key role in cancer cell proliferation, inhibition of chemotherapy-induced apoptosis and drug resistance development. Bortezomib (Velcade, PS-341) was the first proteasome inhibitor to receive...
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Source: Cancer Weekly (2007-05-08)
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