Gene Therapy
Research from Jonsson Comprehensive Cancer Center, Department of Medicine reveals new findings on gene therapy
Published in Cancer Weekly, May 8th, 2007
Data detailed in "AKT activity regulates the ability of mTOR inhibitors to prevent angiogenesis and VEGF expression in multiple myeloma cells" have been presented. According to recent research from the United States, "We recently demonstrated that the mammalian target of rapamycin (mTOR) inhibitor, CCI-779, curtailed the growth of a subcutaneous challenge of multiple myeloma (MM) cells in immunodeficient mice. This antitumor effect was associated with prevention of cell proliferation, induction of apoptosis and inhibition of angiogenesis."
"Interestingly, myeloma tumors with heightened AKT activation were particularly sensitive to a CCI-779-induced antitumor response....
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Source: Cancer Weekly (2007-05-08)
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