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Squamous Cell Carcinoma Risk Factors

Data on squamous cell carcinoma risk factors published by researchers at University of Tokyo

Published in Cancer Weekly, May 8th, 2007

New investigation results, "Genetic polymorphisms of alcohol and aldehyde dehydrogenases, and drinking, smoking and diet in Japanese men with oral and pharyngeal squamous cell carcinoma," are detailed in a study published in Carcinogenesis. According to a study from Tokyo, Japan, "The genetic polymorphisms of aldehyde dehydrogenase-2 (ALDH2), alcohol dehydrogenase-1B (ADH1B, previously called ADH2), and ADH1C (previously called ADH3) affect the metabolism of alcohol. The inactive ALDH2 encoded by ALDH2*1/*2 and the less-active ADH1B encoded by ADH1B*1/*1 increase the risk of esophageal squamous cell carcinoma in East Asian drinkers."

"This case-control study...

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