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Prostate Cancer Prognosis

Data on prostate cancer prognosis described by researchers at University of Tokyo, Department of Urology

Published in Cancer Weekly, June 5th, 2007

A new study, "Increased expression of estrogen-related receptor alpha (ERRalpha) is a negative prognostic predictor in human prostate cancer," is now available. "The nuclear receptor ERRalpha (estrogen-related receptor alpha) is known to modulate the estrogen-signaling pathway, but the biological significance of ERRalpha in the prostate remains unclear. We investigated the expression of ERRalpha in human prostate tissues and cancer cell lines to evaluate the potential roles of the receptor in prostate cancer (PC)," scientists in Tokyo, Japan report.

"Western blot analysis of ERRalpha was performed in three cell lines of human PC (LNCaP, DU145 and PC-3). The expressions...

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