Cancer Gene Therapy
Studies from Princess Margaret Hospital provide new data on cancer gene therapy
Published in Cancer Weekly, June 12th, 2007
Fresh data on cancer gene therapy are presented in the report "One hit, two hits, three hits, more' Genomic changes in the development of retinoblastoma. The childhood eye cancer retinoblastoma is initiated by the loss of both alleles of the prototypic tumor suppressor gene, RB1. However, a large number of cytogenetic and comparative genomic hybridization (CGH) studies have shown that these M1 and M2 mutational events--although necessary for initiation--are not the only genomic changes in retinoblastoma," scientists in Toronto, Canada report.
"Some of these subsequent changes, which we have termed M3 to Mn, are likely crucial for tumor progression not only in...
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Source: Cancer Weekly (2007-06-12)
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