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Cancer

Studies from McGill University in the area of cancer described

Published in Cancer Weekly, June 19th, 2007

Data detailed in "Faithful companions: a proposal for neurooncology trials in pet dogs" have been presented. According to recent research from Montreal, Canada, "Although relatively rare, malignant glioma (MG) is frequently used for testing novel cancer treatments. However, human MG trials have often been initiated on the basis of preclinical models that involve numerous discontinuities with the human disease."

"Below, we discuss various limitations of the mainstay model used in MG preclinical research, the murine orthotopic xenograft. After discussing alternative model systems like transgenic mouse models and canine xenografts, we argue that companion animals with...

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