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Ecole Polytechnique Federale de Lausanne

Migration alert -- How tumor cells home in on the lymphatic system

Published in Cancer Weekly, June 26th, 2007

A Swiss-based research team has published a new mechanistic description of how tumor cells migrate to the lymphatic system in the early stages of tumor metastasis. This new understanding holds significant potential for developing anti-metastasis therapies.

Scientists know that tumor cells spread via the lymphatic system, but they don’t understand the details of how this deadly migration takes place. In the June 2007 issue of the journal Cancer Cell, Ecole Polytechnique Federale de Lausanne (EPFL) Professor Melody Swartz and postdoctoral researcher Jacqueline Shields provide an explanation along with data to support it.

Tumors produce excess fluid...

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