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Glioma Therapy

Research from University of Erlangen yields new findings on glioma therapy

Published in Cancer Weekly, July 17th, 2007

Scientists discuss in "The peroxisome proliferator-activated receptor-gamma agonist troglitazone inhibits transforming growth factor-beta-mediated glioma cell migration and brain invasion" new findings in glioma. "Gliomas are the most common primary tumors of the central nervous system, with glioblastomas as the most malignant entity. Rapid proliferation and diffuse brain invasion of these tumors are likely to determine the unfavorable prognosis," scientists in Erlangen, Germany report.

"Considering its promigratory properties, the transforming growth factor-beta (TGF-beta) signaling pathway has become a major therapeutic target. Analyses of resected glioma tissues...

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