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Breast Cancer Genetics

New data from University of Nottingham illuminate research in breast cancer genetics

Published in Cancer Weekly, July 17th, 2007

A report, "Autoantibodies in breast cancer: their use as an aid to early diagnosis," is newly published data in Annals of Oncology. "There is increasing evidence that the immune system produces a humoral response to cancer-derived antigens. This study assessed the diagnostic potential of autoantibodies to multiple known tumour-associated proteins. Sera from normal controls (n=94), primary breast cancer patients (n=97) and patients with ductal carcinoma in situ (DCIS) (n=40) were investigated for the presence of autoantibodies to p53, c-myc, HER2, NY-ESO-1, BRCA1, BRCA2 and MUC1 antigens by enzyme-linked immunosorbent assay," researchers in Nottingham, the United Kingdom...

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