Cancer

Research from State University of New York provides new data about cancer

Published in Cancer Weekly, July 24th, 2007

A new study, "Superoxide signaling mediates N-acetyl-L-cysteine-induced G1 arrest: regulatory role of cyclin D1 and manganese superoxide dismutase," is now available. According to recent research from the United States, "Thiol antioxidants, including N-acetyl-L-cysteine (NAC), are widely used as modulators of the intracellular redox state. We investigated the hypothesis that NAC-induced reactive oxygen species (ROS) signaling perturbs cellular proliferation by regulating the cell cycle regulatory protein cyclin D1 and the ROS scavenging enzyme Mn-superoxide dismutase (MnSOD)."

"When cultured in media containing NAC, mouse fibroblasts showed G(1) arrest with decreased...

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Source: Cancer Weekly (2007-07-24)

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